Basic premise: In a startling twist, crystal meth helps cure cancer, indirectly.
Why it’s here: Bryan Cranston was, before this show, a decent actor, but not much to write home about. This show made him into a star. More than any other show on this list, it looks hard at society and doesn’t pull punches.
Why it isn’t higher: I haven’t seen the last four episodes yet, and a big part of how successful this show turns out will be how they resolve the character. Skyler is also annoying as hell on occasion.